Transgenic Animals Transgenic animals are being used to study gene mechanism and function, to adapt pig organs to be transferred to humans, to prepare recombinant pharmaceutical proteins in milk and egg white, and to improve breeding and food production.

The medical and biotechnological uses of animal cloning are almost innumerable, as many diseases have been eradicated thanks to the production of these transgenic animals. When inserted successfully, these genes enable an animal to produce (for example) pharmaceutical proteins in its milk, urine, blood, sperm, or eggs, or to grow rejection-resistant organs for transplant. A transgenic animal is one whose genome has been altered by the transfer of a gene or genes from another species or breed. For example, we have transgenic models for diseases such as Alzheimer’s and cancer.

Due to the controversial concept of cloning and scientific testing on animals, there are many questions that revolve around this topic. Moreover, in order to devise a cure for these diseases, the transgenic animals are used as model organisms. animals have been used indicates the wide ranging application of this biotechnology: in medical research, transgenic animals are used to identify the functions of specific factors in complex homeostatic systems through over- or under-expression of a modified gene (the inserted transgene); Credit: Ingrid Moen et alet al., BMC Cancer,12/21 (2012), 1-10.

Drug and Industrial production: Transgenic animals are used for production of proteins such as alpha-1-antitrypsin, produced in liver, used in treatment of emphysema or cystic fibrosis. These transgenic models are used in research for the development of medicines. This process is less expensive than production of protein through culture of human cells 41 . Transgenic animals used for pharmaceutical production are called Transpharmers which produces important human proteins in their milk and eggs … The photo shows two transgenic mice positioned either side of a plain mouse. The transgenic mice have been genetically modified so that they carry a green fluorescent protein which glows green under blue light. From: … Transgenic animals are specially designed to study the role of genes in the development of certain diseases.

Transgenic animals are animals that have been genetically transformed by splicing and inserting foreign (animal or human) genes into their chromosomes.

Transgenic mice have been engineered to express human antibodies (which are superior to murine antibodies for use as drugs) by introducing large segments of human DNA encoding human immunoglobulin genes, and breeding these transgenic animals with strains in which the endogenous immunoglobulin loci are mutated. Transgenic animals are animals that have been cloned.

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