The threat to health comes when the Methanol metabolises into its 1st metabolite Formaldehyde, this occurs when it contacts the enzyme alcohol dehydrogenase (ADH) The largest supply of ADH in the body is in the liver with supplies in 10 other vital sites including the brain and heart and lungs. ( Log Out /  [21][22][23], A 2017 review of metabolic effects by consuming aspartame found that it did not affect blood glucose, insulin, total cholesterol, triglycerides, calorie intake, or body weight, while high-density lipoprotein levels were higher.

He was threatened by the VP of Searle that if he did studies on aspartame and seizures his research funds would be denied. […] av metanol, og både formaldehyd og fenylalanin brytes ned i kroppen i løpet av minutter og forsvinner ut av systemet igjen i sin helhet. Josh/ Jim. “It was just another typical industry whitewash,” he said.”. Here is the FDA report of 92 symptoms from aspartame. So many doctors said that was simply inexcusable. Science, on the other hand, is constantly improving the body of knowledge we have about everything we do science on, by checking and rechecking constantly. I didn’t think you could answer it because you’re defending the manufacturer. So we nicknamed the study the brownie oatmeal study. . But that was also claimed to be in 1987. As to regulatory agencies the FDA revoked the petition until Don Rumsfeld stepped in and “called in his markers”. You’ve linked to EFSA so you’re aware that the safety and hence the ADI of aspartame is currently reviewed, so what’s your point?”. I’ve posted answers for John Garst but unfortunately it hasn’t appeared. It has the highest affinity for crossing the blood-brain barrier of all the circulating amino acids. More information on independent research related to aspartame and seizures can be found at:

She currently lives in Winnipeg, Manitoba, with a determined life mission to help inspire and motivate individuals to critically think about what they put in their bodies and to find balance through nutrition and lifestyle. Initially scheduled to be an 18 month study it is now 2 and a half years late and 200% over budget. These investigations revealed that more than the normal daily recommended amounts are needed (2+ mg), but in these papers increased folate doses ALONE solved the migraine problem [and aspartame was not even involved]. Clearly, regular exposure to a toxic substance such as formaldehyde may worsen, or in some cases contribute to the development of chronic diseases.”. I am aware of the current position of general scientific community on the question of Methanol metabolism and the discounting of the role of formaldehyde in methanol poisoning. Another thing this author appears to be unaware of is the some, but certainly not the majority, of the research listed on both sides of If they want to cover-up they cry hoax! 2) I am perfectly willing to accept that anecdotal evidence is not an end point in science, what I don’t accept is the reluctance of science to engage with the overwhelming evidence of suffering involved and to devote a proportional amount of time and resources to properly investigate it. That’s why I went to New Zealand and Dr. Roberts sent through me the 1000 page medical text so she would know the mechanism by which aspartame triggers or precipitates symptoms and disease. If it was considered a drug then I would think it would have to be labeled as such on all products containing aspartame along with the warnings of the side effects. When I will not concur with you, I come across your supply of your respective belief one that I’m able to basically uncover pleasurable to pay attention to.My experiences with science and naturel have undoubtedly been diverse.I truly admire your pondering.I ought to consider an opposing watch on “vulcanism”, having said that. I asked her how she found out aspartame was poison and she said from ILSI. Would you like to do so now please?

At the same time they tried to remove aspartame because so many are going blind from the free methyl alcohol. Thanks for writing back. If you haven’t heard about the dangers of aspartame, now’s the time to educate yourself. You know it. Now, I don’t doubt that some people’s symptoms disappear when they go off aspartame, but this occurs is because they are so borderline deficient in folate or have some related enzyme issue that is all it takes. We added the information back to the Bressler Report. To anyone who has actually read the research, many of their statements are ridiculous and not backed by the studies they are citing. . [7] A 12 US fluid ounce (355 ml) can of diet soda contains 0.18 grams (0.0063 oz) of aspartame, and for a 75 kg (165 lb) adult, it takes approximately 21 cans of diet soda daily to consume the 3.75 grams (0.132 oz) of aspartame that would surpass the FDA's 50 milligrams per kilogram of body weight ADI of aspartame from diet soda alone. I actually believe many people who report headaches from aspartame, but I suspect that has much to do with their own biochemistry. Fortunately I had brought FDA documents with me and other documents. [25] Because aspartame contains a small amount of phenylalanine, foods containing aspartame sold in the United States must state: "Phenylketonurics: Contains Phenylalanine" on product labels. When a formaldehyde molecule attaches itself to its target it has left the bloodstream and is deemed to have disappeared? Regards. Dr. Walton’s list was simply a preliminary list of what was available in scientific journals at the time.

Independent, unbiased scientists on the other hand have shown in scientific peer reviewed research that aspartame is a killer. Perhaps the alarm bells raised originally were correct about their concern with formaldehyde/formate then, but research starting in 1976 by Tephly and continuing through 1996, http://www.ncbi.nlm.nih.gov/pubmed?term=Tephly%2Cmethanol%2Cmonkeys%2Cfolate has shown the problem wasn’t with these substances, but insufficient vitamins to achieve their destruction. Not good. [4]:94–96[58], Citing data from a Japanese study that had not been available to the members of the PBOI,[59] and after seeking advice from an expert panel that found fault with statistical analyses underlying the PBOI's hesitation, yet argued against approval,[4]:53 FDA commissioner Hayes approved aspartame for use in dry goods. I will post her comments in subsequent comments: Comment #1: reply to Vicky, on January 19, 2013 at 12:48 pm: B12 comes from meat origin, so it is mostly deficient in vegetarians). In some fruit juices, higher concentrations of methanol can be found than the amount produced from aspartame in beverages. I am not a biochemist so would appreciate knowing a bit more about this. Anecdote is not sufficient. Is EFSA now denying responsibility for that?? Contact Dermatitis. Almost 100 per cent of independent scientific peer reviewed research show the problems with aspartame that industry rebuts or ignores as do the regulatory agencies around the world who work with industry. Thank you for the quick response and food for thought. Please note I am not easily intimidated and will not be blinded with science. The problem with aspartame is that although it tastes sweet, it doesn’t actually provide any calories (energy), and the body misses out, making you crave more. Would you also like to talk to Jeanette because she is now our Mission Possible Brookview, Florida? EFSA are making a great HOO Ha that after total hydrolysis, aspartame disappears so cannot be responsible for any adverse effects found. I think we’ve covered it well enough at this point. Upon ingestion, aspartame is broken, converted, and oxidized into formaldehyde in various tissues.

Alemany (the principal investigator did raise doubt, but also didn’t provide sufficient information to impact risk assessment at all. If you think that industry-sponsored always means false, then you shouldn’t be running an organisation. “As another example, you claim that tomato juice contains methanol.commonly known as wood alcohol. So even a small increase in blood phenylalanine will cause a very large increase in brain phenylalanine. Man må opp i aspartamdoser på over 50 mg/kg/dag, altså […]. Over time, methanol can produce the known carcinogen formaldehyde. http://www.holisticmed.com/aspartame/abuse/seizures.html While you see scientific abuse in these studies it shows you can’t do a study on aspartame and have it show safety. How about you? I am placing the responses here to create a new place […]. Interestingly, this was just brought out this morning in an article I will paste it in. Since the folate process is involved in making methyl groups that actually prevent cancer and disease, ethanol use actually enhances cancer and disease, for example http://www.ncbi.nlm.nih.gov/pubmed/22218157 and http://www.ncbi.nlm.nih.gov/pubmed/16508294 and this recent popular US press article, http://www.cbsnews.com/8301-204_162-57569649/alcohol-causes-20000-cancer-deaths-in-the-u.s-annually/. And yet the comments are happily made any how is if it is new and groundbreaking information. PLoS One. We relied on the FDA”. Very interesting read. Dr. Ralph Walton did the research for 60 Minutes on peer reviewed research and funding, Independent studies show that aspartame is unsafe.

Let me just say this: it was not done to see if these individuals were “telling the truth“, but to see if their suspicion – that their reactions are caused by aspartame – are correct. I know the anti-aspartame folks were excited about hearing the results of this, so I think it’s totally relevant. As to the “drug” word issue you raise, see the first two lines of Wikipedia: “a drug is, in the broadest of terms, a chemical substance that has known biological effects on humans or other animals. Also please note that the uncertainty factor is 10-fold, not 10 %.

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