Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place. The production of transgenic sheep has proven difficult compared to the mouse and lower animals.

To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one. The work load is far greater and the rates of success far less by most criteria. The production of transgenic sheep has proven difficult compared to the mouse and lower animals. You can change your cookie settings through your browser. DeepDyve's default query mode: search by keyword or DOI. Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more. Search

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Submitting a report will send us an email through our customer support system. Do not surround your terms in double-quotes ("") in this field. Unfortunately, the low rate of transgenesis for sheep, at about 1% of injected, transferred embryos, means that investigation of the regulation of expression of the transgenes, their phenotypic effects, and optimization of the fusion gene constructs, all of utmost importance to the agricultural industry, can seldom be addressed. Select data courtesy of the U.S. National Library of Medicine. Find any of these words, separated by spaces, Exclude each of these words, separated by spaces, Search for these terms only in the title of an article, Most effective as: LastName, First Name or Lastname, FN, Search for articles published in journals where these words are in the journal name, /lp/springer-protocols/production-of-transgenic-sheep-p0WHH8DO4B. However, the benefits to human and animal health and agricultural productivity are potentially enormous (Ward and Nancarrow, Chapter 5) and support for the continuation of the work is assured. We'll do our best to fix them. Unlimited access to over18 million full-text articles.
However, the benefits to human and animal health and agricultural productivity are potentially enormous (Ward and Nancarrow, Chapter 5) and support for the continuation of the work is assured. They were placed on your computer when you launched this website. Nancarrow, Colin D.; Marshall, James T. A.; Ward, Kevin A. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png, http://www.deepdyve.com/lp/springer-protocols/production-of-transgenic-sheep-p0WHH8DO4B. Require these words, in this exact order. All the latest content is available, no embargo periods. Biotechnology firms and research institutes involved in pharmaceutical development and production use transgenic animals for three different purposes: as a research model, as a test kit, and as pharmaceutical production units.

Their attempt to produce a lung drug in transgenic sheep for Bayer AG was stopped and the company was put up for sale. Bookmark this article. We know now that the mouse may not be a good model for the sheep, an example being the ovine metallothioneinovine growth hormone fusion gene, GH9 ( 1 – 3 ), for which expression and phenotypic effects were quite different for sheep and mice. The work load is far greater and the rates of success far less by most criteria. In sheep, pronuclear microinjection of several hundred copies of the foreign gene into embryos is the only published method used to regularly produce transgenics and it will be the standard by which future methods for incorporation of the transgene are judged. Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly. Reset filters. Thanks for helping us catch any problems with articles on DeepDyve.

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